




A chronobiological night cream designed to support the skin’s natural overnight repair and regeneration processes.
Suitable For
- All Skin Types
- Mature Skin
- Dry Skin
- Skin with Early to Advanced Signs of Ageing.
- Dehydrated Skin
Targets
- Fine Lines & Wrinkles
- Anti-Ageing
- Loss of Firmness
- Cellular Ageing
- Oxidative Stress
- Barrier Weakness
Winner, Harper's Bazaar Best Night Cream for Mature Skin.
An advanced anti-ageing night cream formulated to work in harmony with the skin's natural overnight regenerative cycle. Supreme Night Secret combines chronobiology active Chronodyn and longevity active Juvinity with a nourishing complex of bio-tech extracts and barrier-repair oils to boost cellular energy, protect against cellular ageing and restore firmness and radiance while you sleep.
The science of overnight skin repair.
Chronodyn synchronises with the skin's circadian rhythm during the night phase, when cellular repair is at its peak. By increasing cellular energy (ATP) production, it amplifies the skin's natural recovery process, leaving skin visibly firmer and less fatigued by morning.
Longevity technology at the cell nucleus.
Juvinity targets ageing at the cell nucleus, encouraging skin cells to behave like younger, healthier cells. It limits telomere shortening and oxidative stress to support optimum cell metabolism, so skin not only recovers overnight but ages more slowly over time.
Nourishment and regeneration through the night.
Euglena Gracilis Extract, a nutrient-dense microalgae rich in the unique beta-glucan paramylon, supports the skin's natural defence and repair mechanisms overnight. Date Palm Kernel Extract, rich in isoflavones and phytosterols, stimulates collagen production and improves elasticity. A replenishing blend of plant oils, Hyaluronic Acid and Rapeseed Phytosterols nourishes the skin barrier, delivering intense hydration and protection against oxidative stress. By morning, skin appears smoother, firmer, plumper and more radiant.
"This cream really is the next best thing to booking an appointment at Dr Sebagh's London clinic." - Net A Porter







Supreme Night Secret
Compare With...
-
Cellular Longevity Overnight Cream
-
Prevents Telomere Shortening
-
Firms, Tones & Erases Fatigue
-
Restructures & Repairs the Skin Barrier
-
Targeted Moisture for Mature & Menopausal Skin
-
Restructures & Replenishes the Skin Barrier
-
Boosts Collagen Synthesis
-
Soothes Redness & Sensitivity
Blog posts

Male skin after 50 is biologically distinct — and it requires a different approach. Dr. Sebagh answers a reader's question with a five-step routine built for men in their 50s: from a foaming cleans...

Discover the Dr Sebagh Supreme Range, an advanced anti-ageing skincare system designed to support skin longevity through peptides, antioxidants and innovative technologies that protect, repair and ...

Night is when the skin repairs itself, making the right night cream essential for long-term skin health. This guide explains how to choose the best night cream based on your skin type, from balance...

The Serum Bar is Dr Sebagh’s collection of five targeted serums designed to address hydration, barrier support, expression lines, prevention and long-term regeneration. In this guide, discover the ...

Skin changes daily in response to stress, hormones and environment. In this expert guide, Dr Sebagh explains how to understand your skin’s changing needs, how stress affects circulation and glow, a...























