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Supreme Night Secret Sample
Supreme Night Secret Sample
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Instant Fix Eye Lift Gel Sample
Instant Fix Eye Lift Gel Sample
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Supreme Day Cream Sample
Supreme Day Cream Sample
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Deep Exfoliating Mask Sample
Deep Exfoliating Mask Sample
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High Maintenance Cream Sample
High Maintenance Cream Sample
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Vitamin C Brightening Primer SPF15 Sample
Vitamin C Brightening Primer SPF15 Sample
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Deep Exfoliating Mask Sensitive Skin Sample
Deep Exfoliating Mask Sensitive Skin Sample
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Skin Perfecting Mask Sample
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Rose de Vie Cream Cleanser Sample
Rose de Vie Cream Cleanser Sample
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Skin Perfecting Cream Sample
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Replenishing Cream Sample
Replenishing Cream Sample
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Vital Cream Sample
Vital Cream Sample
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Peptide Skincare Formulas

What Are Peptides and Why Do They Work?

Peptides are the foundation of high-performance anti-ageing skincare. These short chains of amino acids are the building blocks of collagen, elastin and keratin, the proteins responsible for your skin’s firmness, elasticity and smooth texture. As we age, natural peptide production slows, accelerating the formation of fine lines, wrinkles and loss of definition.

Dr Sebagh’s peptide formulas go beyond the ordinary. Each product in this collection is developed with clinically-substantiated peptide complexes, including Palmitoyl Pentapeptide-4, Micro-Molecular Collagen Peptides and Dr Sebagh’s proprietary BioPeptide ETF, formulated at concentrations that deliver measurable results. No filler. No compromise. Just science that works.

From the clinics of London’s Chandos House to your daily routine, these are the formulas Dr Sebagh trusts with the skin of his most discerning patients.

 

All Skin TypesProduct image of Dr Sebagh Serum Repair, a hyaluronic acid and peptide serum designed to hydrate, plump and repair skinDr Sebagh serum repair bottle held by a person with text indicating skin repair and hydration benefits.
HydrationAnti-ageing
Serum Repair Hyaluronic acid serum with collagen-boosting peptide for deep hydration,...
Sale priceFrom £22.00
(4.7)
Award WinnerDr Sebagh Supreme Maintenance Youth Serum 30ml bottle with pipetteSupreme Maintenance Youth Serum 30ml, Dr Sebagh peptide anti-ageing serum
Supreme Maintenance Youth Serum A lightweight daily peptide serum that firms, brightens and defends skin...
Sale priceFrom £22.00
(4.5)

Dr Sebagh's Blackhead Protocol

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Award WinnerPlatinum Gold ElixirWoman holding a skincare serum with text about wrinkle reduction on a beige background
Platinum Gold Elixir Advanced Peptide Serum to Smooth Wrinkles, Lift, Firm & Restore Radiance
Sale priceFrom £55.00
(4.3)
Dr Sebagh Deep Exfoliating Mask jar for glow-boosting skin exfoliationModel holding Dr Sebagh Deep Exfoliating Mask jar beneath her chin, showing smooth, glowing skin
Deep Exfoliating Mask An award-winning lactic and azelaic acid mask for brighter, smoother, cl...
Sale priceFrom £20.00
(4.2)
Dr Sebagh Deep Exfoliating Mask Sensitive Skin jar with black lid on white backgroundModel holding Dr Sebagh Deep Exfoliating Mask Sensitive Skin jar against her jaw
Deep Exfoliating Mask Sensitive Skin Gentle Exfoliating Face Mask for Sensitive Skin with AHA & Azelaic Acid ...
Sale priceFrom £20.00
(5.0)
Award WinnerSupreme Neck LiftDr Sebagh Supreme Neck Lift cream jar shown on a white background with marketing text describing multi-active lifting treatment benefits.
Supreme Neck Lift Powerful neck-lifting and firming cream to tighten sagging skin, smooth ...
Sale priceFrom £108.00 Regular price£120.00
(4.7)
Award WinnerInstant Fix Eye Lift Gel – Clear Pump BottleInstant Eye Lift Gel before and after under eye transformation
Instant Fix Eye Lift Gel A weightless gel that instantly tightens and lifts the look of the eye c...
Sale priceFrom £46.80 Regular price£52.00
(4.7)
Award Winner Multi-Peptide FormulaCooling Applicator Technology De-Puff Eye TreatmentDe-Puff Eye Treatment
De-Puff Eye Treatment Voted Best Eye De-Puffer, InStyle. A precision multi-peptide eye cream f...
Sale priceFrom £50.40 Regular price£56.00
(4.8)
Replenishing CreamReplenishing Cream
Replenishing Cream High-performance moisturiser for menopausal and mature skin. Targets dry...
Sale priceFrom £64.80 Regular price£72.00
(5.0)
Dr Sebagh Extreme Maintenance Cream 50ml in a frosted glass jar with a black lidDr Sebagh Extreme Maintenance Cream shown on a clean white background with descriptive text highlighting intensive hydration, barrier repair, and suitability for dry, sensitive, and fragile skin.
Extreme Maintenance Cream Ultra-rich hydrating cream that repairs dryness, restores comfort and st...
Sale priceFrom £30.00
(4.3)
Luminous Glow CreamLuminous Glow Cream
Luminous Glow Cream Oil-free moisturiser with instant radiance boost, hyaluronic acid hydrat...
Sale priceFrom £28.00
(4.3)
Award WinnerDr Sebagh Instant Fix Eye Lift Gel beside a red and white striped Christmas crackerInstant Fix Eye Lift Gel – Clear Pump Bottle
Instant Fix Eye Lift Gel (15ml) Christmas Cracker Fast-acting eye-lift gel that tightens, reduces puffiness, smooths wrink...
Sale price£46.80 Regular price£52.00
All Skin TypesDr Sebagh Serum Repair 20ml beside a red and white striped Christmas crackerProduct image of Dr Sebagh Serum Repair, a hyaluronic acid and peptide serum designed to hydrate, plump and repair skin
HydrationAnti-ageing
Serum Repair (20ml) Christmas Cracker Hyaluronic acid serum with collagen-boosting peptide for deep hydration,...
Sale price£64.80 Regular price£72.00

Frequently asked questions

Q: What are peptides in skincare?

A: Peptides are short chains of amino acids that act as messengers in the skin, signalling cells to produce more collagen, elastin and hyaluronic acid. In skincare, peptides are used as active ingredients to reduce fine lines, firm skin and accelerate repair. Unlike retinol, peptides work without irritation, making them suitable for all skin types.

Q: What do peptides do for your skin?

A: Peptides stimulate the skin’s natural collagen synthesis, helping to restore firmness and smooth the appearance of wrinkles. Certain peptides, such as Palmitoyl Pentapeptide-4, have been shown to reduce the depth of fine lines measurably within weeks of use. Others help strengthen the skin barrier, improve moisture retention and accelerate post-treatment recovery.

Q: Which Dr Sebagh products contain peptides?

A: Several Dr Sebagh formulas are built around clinically-active peptide complexes: Serum Repair contains Palmitoyl Pentapeptide-4 and Micro-Molecular Collagen Peptide for deep hydration and wrinkle reduction; Supreme Maintenance Youth Serum features three specialised anti-ageing peptides to stimulate, repair and strengthen the collagen matrix; and Crème Vital harnesses the BioPeptide ETF to prevent premature ageing. All are available in this collection.

Q: Are peptides better than retinol?

A: Peptides and retinol work differently but are highly complementary. Retinol accelerates cell turnover but can cause sensitivity; peptides build collagen and firm skin without irritation. For sensitive or mature skin, or anyone undergoing cosmetic treatments, peptides are often the preferred choice. Used together, they can deliver enhanced anti-ageing results, as practised at the Dr Sebagh clinic.