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Retinol 101
CollagenNov 7, 20225 min read

Retinol 101

 

Why Dr Sebagh Retinol Night Repair Is the Best Retinol for Sensitive, Mature & Menopausal Skin

Retinol is one of the most clinically proven skincare ingredients in the world, a vitamin A derivative celebrated for its ability to slow, correct and visibly reverse the signs of ageing, while treating concerns from hyperpigmentation to breakouts. Yet for many, retinol still feels intimidating, especially for sensitive or menopausal skin.

Before creating the award-winning Dr Sebagh Retinol Night Repair, Dr Sebagh and his team conducted a consumer survey to uncover the myths and misunderstandings surrounding this extraordinary molecule. The results were striking — and they shaped a formula that delivers powerful results with minimal irritation, making it suitable even for sensitive and hormonally changing skin.

This edition of Skin Secrets explains exactly how retinol works, why Dr Sebagh’s formula is unique, and how to use it for healthy, radiant, age-defying skin.

Understanding Retinol Strengths (and Why Most People Get It Wrong)

90% of people surveyed did not understand the difference between retinol strengths.

All topical vitamin A (retinoids) ultimately work by converting into retinoic acid, the active form already naturally present in our skin. Stronger retinoids convert more quickly; gentler forms convert more slowly.

A quick breakdown of the retinoid family:

  • Tretinoin (Retin-A): Prescription-only; already in its active form; strongest and most irritating.

  • Retinol: The most studied over-the-counter form. Converts in two steps:
    retinol → retinaldehyde → retinoic acid.

  • Retinol esters (e.g., retinyl palmitate): Convert in three steps and are therefore weaker and less effective.

The higher the percentage of retinol, the more active retinoic acid your skin ultimately receives, but: higher doesn’t mean better if your skin becomes inflamed, dry or reactive.

That is where expert formulation truly matters.

How Retinol Works: The Science Behind Vitamin A

Retinol is exceptional because it works on multiple layers of the skin.

Retinol on the Epidermis: Smoother, Brighter, Clearer Skin

  • Boosts cell turnover

  • Smooths texture

  • Softens fine lines

  • Brightens dullness

  • Helps fade dark spots and post-acne marks

This is a gradual exfoliation — different from AHAs/BHAs — driven by increased renewal, not surface peeling.

Retinol on the Dermis: Collagen, Firmness & Anti-Ageing

Retinol is one of the few cosmetic ingredients proven to penetrate the dermis, where it helps:

  • Increase collagen

  • Stimulate elastin

  • Improve firmness and elasticity

  • Reduce wrinkles

  • Strengthen the skin structure

Additional benefits:

  • Neutralises free radicals from UV exposure

  • Regulates melanocytes (pigment-producing cells)

  • Helps prevent clogged pores and breakouts

  • Balances hydration and sebum levels

No other cosmetic ingredient offers such a comprehensive approach to ageing well.

Why Dr Sebagh Retinol Night Repair Is Different — and Better

Many retinol products are simply too aggressive, especially for sensitive, menopausal or barrier-impaired skin.
Dr Sebagh Retinol Night Repair was created to solve that.

Built-in sensitivity support

Rather than relying on high percentages alone, Dr Sebagh formulated a high-performance yet tolerant retinol supported by:

  • Non-comedogenic oils

  • Vitamin E (antioxidant protection)

  • Squalane (skin-identical moisturising lipid)

This synergy helps buffer retinol’s effects, minimising dryness or irritation — even during the traditional “purging” period.

Crystal Tears (Lakesis): The Cellular Longevity Ingredient

A standout ingredient, Lakesis, derived from the resin of the Pistacia tree, acts on FOXO proteins: key regulators of cellular longevity, detoxification and repair.

In clinical studies, this ingredient has been shown to help:

  • Revitalise tired, ageing or menopausal skin

  • Increase collagen synthesis

  • Improve firmness and facial contours

  • Support cellular renewal

This makes Retinol Night Repair not only a retinol, but a next-generation anti-ageing night serum.

How to Use Retinol Night Repair for Maximum Results

1. Introduce gradually

To avoid irritation:

  • Week 1: once a week

  • Week 2–3: twice weekly

  • Week 4 onward: up to five nights a week as tolerated

Slow and steady builds long-term tolerance.

2. Night-only

Retinol degrades in sunlight (photodecomposition), losing efficacy and potentially generating free radicals.
Always apply at night and use broad-spectrum sunscreen every morning.

3. You can use retinol in summer

There is a persistent myth that retinol should be stopped in warmer months.
In reality: retinol + SPF = safe, effective, and prevents pigmentation, even in summer.

Who should use retinol?

Only 30% of people currently use a retinol — but dermatologists commonly recommend beginning in your mid-twenties, especially if you experience:

  • Breakouts

  • Pigmentation

  • Early fine lines

  • Dullness

For menopausal skin — where collagen drops rapidly — retinol becomes even more transformative.

What NOT to mix with retinol

50% of people were unsure about ingredient compatibility.

Avoid using retinol on the same night as:

Instead:

  • Use acids on alternate nights, or in the morning.

  • Use vitamin C in the morning for antioxidant protection.

And, as always: SPF 15–50 is essential every morning.

Retinol for Sensitive & Menopausal Skin: Why Tolerance Matters

50% of people worry about irritation.
20% avoid retinol altogether due to sensitive skin.

Dr Sebagh specifically designed Retinol Night Repair to eliminate this fear.

Barrier-supporting hydration built in

The formula works with the skin — not against it — thanks to:

  • Squalane (strengthens barrier)

  • Vitamin E (soothing antioxidant)

  • Lightweight non-pore-clogging oils (comfort without congestion)

Optional extra hydration: The Dr Sebagh Retinol Sandwich

Sensitive or menopausal skin often benefits from layering:

  1. After cleansing: apply Serum Repair (hyaluronic acid) to damp skin

  2. Allow it to absorb

  3. Apply Retinol Night Repair

  4. Seal with a moisturiser:

This “Retinol Sandwich” deeply hydrates, stabilises retinol penetration and minimises irritation — making the routine suitable for even reactive skin types.

Discover all Dr Sebagh moisturisers and find one suitable for your skin type.


The Takeaway: Retinol Works. But Dr Sebagh Retinol Night Repair Works Smarter.

Retinol is one of the most transformative ingredients in dermatology — but the key to success is the right formula, not the highest percentage.

Dr Sebagh Retinol Night Repair is expertly engineered to:

  • Deliver visible anti-ageing results

  • Improve firmness and radiance

  • Support menopausal and sensitive skin

  • Minimise irritation

  • Strengthen the skin barrier

  • Work in harmony with your skin’s natural night-time regeneration

This is retinol for real skin, not just resilient skin, and one of the most advanced vitamin A treatments available without prescription.

Ready to experience the most intelligent, irritation-free retinol?
Discover Dr Sebagh Retinol Night Repair — the expert-formulated vitamin A serum designed for all skin types including sensitive, mature and menopausal skin.

Shop Retinol Night Repair

Watch: Dr Sebagh Explains Retinol & How to Use It Safely

 

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